{"product_id":"slu-pp-332","title":"SLU-PP-332","description":"\u003cp dir=\"auto\"\u003e\u003cstrong\u003eProduct Description\u003c\/strong\u003e SLU-PP-332 is a potent pan-estrogen-related receptor (ERR) agonist that activates ERRα, ERRβ, and ERRγ (with highest potency at ERRα, EC₅₀ ≈ 98 nM). Supplied as ≥98% pure lyophilized powder (HPLC\/MS verified), it is designed for laboratory studies on mitochondrial biogenesis, energy metabolism, exercise mimetics, and metabolic regulation.\u003c\/p\u003e\n\u003cp dir=\"auto\"\u003e\u003cstrong\u003eKey Research Mechanism\u003c\/strong\u003e SLU-PP-332 binds to ERR nuclear receptors, stabilizing their active conformation and enhancing recruitment of coactivators such as PGC-1α. This triggers gene expression programs that mimic aerobic exercise, increasing mitochondrial function, fatty acid oxidation, oxidative phosphorylation, and cellular energy expenditure.\u003c\/p\u003e\n\u003cp dir=\"auto\"\u003e\u003cstrong\u003ePrimary Research Areas\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul dir=\"auto\"\u003e\n\u003cli\u003eExercise mimetic effects and mitochondrial biogenesis in muscle cells\u003c\/li\u003e\n\u003cli\u003eMetabolic health \u0026amp; obesity models (reduced fat mass and improved glucose tolerance in preclinical studies)\u003c\/li\u003e\n\u003cli\u003eEnergy expenditure, fatty acid oxidation, and endurance pathway research\u003c\/li\u003e\n\u003cli\u003eMitochondrial efficiency and age-related metabolic decline\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp dir=\"auto\"\u003e\u003cstrong\u003eIntended Use\u003c\/strong\u003e For \u003cem\u003ein vitro\u003c\/em\u003e and \u003cem\u003ein vivo\u003c\/em\u003e research only. Not for human or veterinary use. This product is sold strictly for scientific and laboratory investigation. Researchers must follow all institutional and regulatory guidelines. Not evaluated by the FDA.\u003c\/p\u003e","brand":"AxisBiotech+","offers":[{"title":"5 mg","offer_id":40687188410497,"sku":null,"price":169.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0596\/2652\/0705\/files\/SLU-PP.webp?v=1779977152","url":"https:\/\/axisbiotech.com\/products\/slu-pp-332","provider":"AxisBiotech+","version":"1.0","type":"link"}