Thymosin α1

Product Description Thymosin α1 is a synthetic 28-amino acid peptide derived from prothymosin alpha that acts as a potent immune modulator. Supplied as ≥98% pure lyophilized powder (HPLC/MS verified), it is designed for laboratory studies on immune system regulation, T-cell maturation, and innate/adaptive immune responses.

Key Research Mechanism Thymosin α1 binds to Toll-like receptors (TLR2 and TLR9) on dendritic cells and myeloid cells, activating NF-κB and IRF3 signaling pathways. This promotes T-cell differentiation, cytokine production (including IFN-γ and IL-2), dendritic cell maturation, and overall enhancement of cell-mediated immunity while reducing apoptosis in immune cells.

Primary Research Areas

• Immune modulation and T-cell / dendritic cell function studies
• Vaccine adjuvant and antiviral response research
• Cancer immunotherapy and tumor microenvironment investigations
• Autoimmune conditions, inflammation, and sepsis-related immune support models

Intended Use For in vitro and in vivo research only. Not for human or veterinary use. This product is sold strictly for scientific and laboratory investigation. Researchers must follow all institutional and regulatory guidelines. Not evaluated by the FDA.