IGF-1 LR3

Product Description IGF-1 LR3 is a synthetic, long-acting analog of human Insulin-like Growth Factor-1 (IGF-1). Modified with an arginine substitution at position 3 and a 13-amino acid N-terminal extension, it offers significantly extended half-life and potency compared to native IGF-1. Supplied as ≥98% pure lyophilized powder (HPLC/MS verified), it is designed for laboratory studies on cell growth, tissue repair, and metabolic signaling.

Key Research Mechanism IGF-1 LR3 acts as a potent agonist of the IGF-1 receptor with low affinity for IGF-binding proteins (IGFBPs). This enables prolonged receptor activation, stimulating pathways involved in protein synthesis, cell proliferation, differentiation, and glucose uptake while promoting lipolysis in research models.

Primary Research Areas

• Muscle growth, hypertrophy, and tissue repair models
• Cellular proliferation, differentiation, and regeneration studies
• Metabolic regulation and body composition research
• Recovery processes and satellite cell activation in preclinical models

Intended Use For in vitro and in vivo research only. Not for human or veterinary use. This product is sold strictly for scientific and laboratory investigation. Researchers must follow all institutional and regulatory guidelines. Not evaluated by the FDA.