Retatrutide

Product Description Retatrutide is a synthetic 39-amino acid peptide that acts as a triple agonist of the GLP-1 receptor (GLP-1R), glucose-dependent insulinotropic polypeptide receptor (GIPR), and glucagon receptor (GCGR). Supplied as ≥98% pure lyophilized powder (HPLC/MS verified), it is designed for laboratory studies on metabolic regulation, energy expenditure, appetite control, and body composition research.

Key Research Mechanism Retatrutide simultaneously activates GLP-1R, GIPR, and GCGR pathways. This balanced triple agonism enhances insulin secretion, suppresses appetite, increases energy expenditure via glucagon signaling, and promotes lipolysis and fat oxidation while improving glycemic control in research models.

Primary Research Areas

• Obesity and weight management models (significant reductions in body weight and adiposity)
• Type 2 diabetes and insulin sensitivity studies
• Energy expenditure, lipid metabolism, and appetite regulation research
• Multi-receptor incretin and glucagon pathway investigations

Intended Use For in vitro and in vivo research only. Not for human or veterinary use. This product is sold strictly for scientific and laboratory investigation. Researchers must follow all institutional and regulatory guidelines. Not evaluated by the FDA.