VIP

Product Description Vasoactive Intestinal Peptide (VIP) is a 28-amino acid neuropeptide belonging to the glucagon/secretin superfamily. It acts as a potent neurotransmitter, neuromodulator, and hormone with broad physiological effects. Supplied as ≥98% pure lyophilized powder (HPLC/MS verified), it is designed for laboratory studies on vasodilation, immune modulation, neuroendocrine function, and inflammatory pathways.

Key Research Mechanism VIP binds to VPAC1 and VPAC2 G-protein-coupled receptors, activating adenylate cyclase and increasing intracellular cAMP levels. This leads to smooth muscle relaxation, vasodilation, immunomodulation (promoting anti-inflammatory and tolerogenic responses), and regulation of secretion in the gut, lungs, and other tissues.

Primary Research Areas

• Neuroprotection, neurotransmission, and circadian rhythm studies
• Immune modulation, inflammation, and autoimmune response models
• Vasodilation, smooth muscle relaxation, and cardiovascular research
• Gastrointestinal motility, secretion, and gut barrier integrity investigations

Intended Use For in vitro and in vivo research only. Not for human or veterinary use. This product is sold strictly for scientific and laboratory investigation. Researchers must follow all institutional and regulatory guidelines. Not evaluated by the FDA.